MG-115 (Proteasome Inhibitor)

Product Sizes

5 mg

£304.00

ECH-882-10-5MG

About this Product

SKU:: ECH-882-10
CAS Number:: 133407-86-0
Extra Details:: CAS Number: 133407-86-0 \nMolecular Weight: 461.29 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Z-Leu-Leu-Nva-CHO \nSequence (1-letter): Z-LL(Nva)-CHO \nStorage: -20 ?C or below \n \nMG-115 (Z-Leu-Leu-Nva-CHO) is a potent, cell permeable inhibitor of the 20S proteosome. It forms a reversible hemiacetal adduct and can also inhibit cathepsins and calpains. It reduces degradation of ubiquitinated proteins and blocks proteolytic conversion of protein precursors. MG-115 is known to induce the heat shock response and apoptosis. \nReferences \nRock, K.L., Gramm, C., Rothstein, L.,?et al. (1994) "Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules".?Cell?78,?761-771., Echelon
Molecular Weight:: 461.29
Sequence:: Z-Leu-Leu-Nva-CHO \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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