Caspase 3 (Apopain) Inhibitor

Product Sizes

5 mg

£370.00

ECH-864-20-5MG

About this Product

SKU:: ECH-864-20
CAS Number:: 184179-08-6
Extra Details:: CAS Number: 184179-08-6 \nMolecular Weight: 502.19 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Asp-Glu-Val-Asp-CHO \nSequence (1-letter): Ac-DEVD-CHO \nStorage: -20 ?C or below \nSolubility: 13.7 mg/ml in DMSO \n \nCaspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent, reversible inhibitor of caspase-3 (Ki < 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent. \nReferences \n1. Talanian, R.V. et al (1997) ?Substrate Specificities of Caspase Family Proteases? 272 (15): 9677?9682. \n2. Godinat, A. et al. (2013) ?A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice? ACS Chemical Biology 8 (5): 987-999., Echelon
Molecular Weight:: 502.19
Sequence:: Ac-Asp-Glu-Val-Asp-CHO \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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