Caspase 1 (ICE) Inhibitor

Product Sizes

5 mg

ECH-864-15-5MG

About this Product

SKU:: ECH-864-15
CAS Number:: 143313-51-3
Extra Details:: CAS Number: 143313-51-3 \nMolecular Weight: 492.22 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Tyr-Val-Ala-Asp-CHO \nSequence (1-letter): Ac-YVAD-CHO \nStorage: -20 ?C or below \nSolubility: DMSO (5 mg/ml), water (5 mg/ml), ethanol (30 mg/ml), DMF (30 mg/ml) \n \nN-Ac-Tyr-Val-Ala-Asp-CHO (Ac-YVAD-CHO) is a synthetic peptide that reversibly and selectively inhibits interleukin-1? converting enzyme (ICE; Caspase-1). Caspase-1 is a pro-inflammatory cytokine and like other caspase inhibitors, interferes with the initiation of apoptosis and has numerous possible clinical applications \nReferences \n1. Cerretti D.P., et al. (1992) ?Molecular cloning of the interleukin-1 beta converting enzyme? Science 256: 97?100. \n2.Thornberry N.A. et al. (1992) ?A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes? Nature 356: 768?774., Echelon
Molecular Weight:: 492.22
Sequence:: Ac-Tyr-Val-Ala-Asp-CHO \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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