Ac-YVAD-CHO Caspase 1 (ICE) Inhibitor

Product Sizes

5 mg

ECH-864-15-5MG

About this Product

SKU:: ECH-864-15
Extra Details:: CAS Number: 143313-51-3Molecular Weight: 492.22Salt Form: N/APurity: >95%Sequence (3-letter): Ac-Tyr-Val-Ala-Asp-CHOSequence (1-letter): Ac-YVAD-CHOStorage: -20 °C or belowSolubility: DMSO (5 mg/ml) water (5 mg/ml) ethanol (30 mg/ml) DMF (30 mg/ml)N-Ac-Tyr-Val-Ala-Asp-CHO (Ac-YVAD-CHO) is a synthetic peptide that reversibly and selectively inhibits interleukin-1B Beta converting enzyme (ICE; Caspase-1). Caspase-1 is a pro-inflammatory cytokine and like other caspase inhibitors interferes with the initiation of apoptosis and has numerous possible clinical applicationsReferences1. Cerretti D.P. et al. (1992) aoeMolecular cloning of the interleukin-1 beta converting enzymea Science 256: 97-100.2.Thornberry N.A. et al. (1992) aoeA novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytesa Nature 356: 768-774.
Molecular Weight:: 492.22
Sequence:: Ac-Tyr-Val-Ala-Asp-CHO
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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