Caspase 6 (Mch2) Substrate, fluorogenic

Product Sizes

5 mg

£304.00

ECH-863-52-5MG

25 mg

£948.00

ECH-863-52-25MG

About this Product

SKU:: ECH-863-52
Extra Details:: Molecular Weight: 727.27 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Val-Glu-Ile-Asp-AFC \nSequence (1-letter): Ac-VEID-AFC \nStorage: -20 ?C or below \nSolubility: 20 mM in DMSO or DMF \n \nAc-VEID-AFC is a fluorogenic substrate for caspase 6 (Mch-2?), a member of the cysteine-aspartate protease family, which play a central role in the execution-phase of apoptosis. The excitation/emission maximum of AFC is 400/505 nm, respectively. Ac-VEID-AFC is based on lamin A site of cleavage. \nReferences \n1. LeBlanc, A. et al. (1999) ?Caspase-6 Role in Apoptosis of Human Neurons, Amyloidogenesis, and Alzheimer?s Disease? J. Biol. Chem. 274: 23426-23436. \n2. Guo, R-F. et al. (2000) ?Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis? J. Clin. Invest. 106(10): 1271?1280., Echelon
Molecular Weight:: 727.27
Sequence:: Ac-Val-Glu-Ile-Asp-AFC \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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