Ac-Val-Asp-Gln-Gln-Asp-pNA (Caspase 2 (ICH-1) Substrate)
Product Sizes
5 mg
ECH-860-44-5MG
25 mg
ECH-860-44-25MG
About this Product
- SKU:
- ECH-860-44
- Extra Details:
- Molecular Weight: 765.29Salt Form: TFAPurity: >96%Sequence (3-letter): Ac-Val-Asp-Gln-Gln-Asp-pNASequence (1-letter): Ac-VDQQD-pNAStorage: -20 °C or belowAc-Val-Asp-Gln-Gln-Asp-pNA is a colorimetric substrate for Caspase 2. Caspase 2 part of the ICH-1 sub-family is a cysteine protease with a poorly defined role in apoptosis. It associates with several apoptotic proteins such as death effector filament-forming Ced-4-like apoptosis protein (DEFCAP) RIP-associated Ich-1/Ced-3-homologue protein with a death domain (RAIDD) and apoptosis repressor with caspase recruitment domain (ARC). Caspase 2 can be activated by the PIDDosome formed by the association of PIDD1 and CRADD. Recent work demonstrates that Caspase-2 resides in the mitochondria and is essential for stress-induced apoptosis.Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.
- Molecular Weight:
- 765.29
- Sequence:
- Ac-Val-Asp-Gln-Gln-Asp-pNA
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:https://www.echelon-inc.com/product/ac-val-asp-gln-gln-asp-pna-caspase-2-ich-1-substrate-colorimetric/
