Furin Inhibitor II

Product Sizes

1 mg

£113.00

ECH-855-10-1MG

5 mg

£228.00

ECH-855-10-5MG

25 mg

£689.00

ECH-855-10-25MG

About this Product

SKU:: ECH-855-10
CAS Number:: 673202-67-0
Extra Details:: CAS Number: ?673202-67-0 \n \nMolecular Weight: 953.63 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 \nSequence (1-letter): rrrrrr-NH2 \nStorage: -20 ?C or below \nSolubility: 20% acetonitrile/water 1 mg/mL \n \nFurin inhibitor II, as the name implies, inhibits furin (Ki = 0.106 for purified furin). Furin is an enzyme belonging to the subtilisin-like proprotein convertase family which process precursor proteins into biologically active products. \nRepresentative substrates include von Willebrand factor, TGF?-1 precursor, MMP-1, gp160, proparathyroid hormone and proalbumin. Peptide contains all D-amino acids; also called Hexa-D-Arg or Hexa-D-Arginine or (D-Arg)6-NH2 \nReferences \n1.Cameron, A. et al. (2000) ?Polyarginines Are Potent Furin Inhibitors? J. Biol. Chem. 275: 36741-36749. \n2.Henrich, S. et al. (2005) ?Proprotein Convertase Models based on the Crystal Structures of Furin and Kexin: Explanation of their Specificity? J. Mol. Biol. 345 (2): 211?227., Echelon
Molecular Weight:: 953.63
Sequence:: D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

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