ADAM substrate

Product Sizes

1 mg

£578.00

ECH-825-15-1MG

5 mg

£2023.00

ECH-825-15-5MG

About this Product

SKU:: ECH-825-15
Extra Details:: Molecular Weight: 1760.93 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): H-Glu(EDANS)-Lys-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dabcyl)-NH2 \nSequence (1-letter): (Glu(EDANS))KPAKFFRL(Lys(Dabcyl))-NH2 \nStorage: -20 ?C or below \n \nADAM substrate is a FRET based fluorogenic substrate for ADAM metalloproteinases. The substrate contains the acceptor DABCYL, which acts as an acceptor for the donor, EDANS. Activity is quantified by release of fluorescent EDANS which excites at 365 nm and emits at 490 nm. ADAMs cleave extracellular portions of transmembrane proteins such as HER2 which is subsequently activated. Some ADAMS are also known as sheddases., Echelon
Molecular Weight:: 1760.93
Sequence:: H-Glu(EDANS)-Lys-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dabcyl)-NH2 \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

Basket