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Proteins and Peptides

Neurotensin, human

Product Sizes
1 mg
£131.00
ECH-631-27-1MG
5 mg
£214.00
ECH-631-27-5MG
About this Product
SKU:
ECH-631-27
CAS Number:
58889-67-1
Extra Details:
CAS Number: 58889-67-1 \nMolecular Weight: 1671.9 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH (Glp = Pyroglutamic acid) \nSequence (1-letter): (Glp)LYENKPRRPYIL-OH \nStorage: -20 ?C or below \nSolubility: water (0.7 mg/mL) \n \nNeurotensin (NT) is a brain and gastrointestinal peptide with many central and peripheral functions. It is a neurotransmitter-like hypothalamic peptide that lowers blood pressure, increases vascular permeability, and increases blood levels of glucagon, glucose, growth hormone, and prolactin in rats. NT acts as modulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally, NT acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular system \nReferences \n1. Carraway, R. and Leeman, S.E. (1973) ?The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami? J. Biol. Chem. 248: 6854-6861. \n2. White, J.F. et al. (2012) ?Structure of the agonist-bound neurotensin receptor? Nature 490 (7421): 508-513. \n3. Tanaka, K., Masu, M. and Nakanishi, S. (1990) ?Structure and functional expression of the cloned rat neurotensin receptor? Neuron 4 (6,): 847?854., Echelon
Molecular Weight:
1671.9
Sequence:
Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH (Glp = Pyroglutamic acid) \n
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides