Endothelin 3, cyclic (human, mouse, rabbit, rat)
Product Sizes
0.5 mg
£413.00
ECH-335-10-0.5MG
1 mg
£621.00
ECH-335-10-1MG
About this Product
- SKU:
- ECH-335-10
- CAS Number:
- 117399-93-6
- Extra Details:
- CAS Number: 117399-93-6 \nMolecular Weight: 2645.16 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Cys1-Cys15, Cys3-Cys11) \nSequence (1-letter): CTCFTYKDKECVYYCHLDIIW-OH \nStorage: -20 ?C or below \nSolubility: water >1 mg/mL \n \nEndothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. Endothelin-3 is an endogenous neuropeptide and potent vasoconstrictor. Endothelin-3 has been reported to attenuate thrombin-evoked aggregation of human platelets, acts as a potent stimulator of interleukin-6 production by endothelial cell lines, activates phospholipase C in fibroblasts expressing ETA receptors and induces the production of VEGF. \nReferences \n1. Baynash, A.G. (1994) ?Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons? Cell 79 (7): 1277?1285. \n2. Matsumoto, H. et al. (1989) ?Abundance of endothelin-3 in rat intestine, pituitary gland and brain? 164 (1): 74-80. \n3. Sakamoto, A. et al. (1991) ?Cloning and functional expression of human cDNA for the ETB endothelin receptor? Biochem. Biophys. Res. Commun. 178 (2): 656?663, Echelon
- Molecular Weight:
- 2645.16
- Sequence:
- Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Cys1-Cys15, Cys3-Cys11) \n
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:https://www.echelon-inc.com/product/endothelin-3-human-mouse-rabbit-rat-cyclic-et-3-human-mouse-rabbit-rat-cyclic/
