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Proteins and Peptides

Recombinant Human IGF-2

Product Sizes
50ug
£232.00
Y12441H-50UG
1mg
£1274.00
Y12441H-1MG
About this Product
SKU:
Y12441H
Application:
Bioactivity
Extra Details:
IGF-2 (Insulin-like Growth Factor 2) is an important single-chain polypeptide growth factor composed of 67 amino acids with a molecular weight of approximately 7.5 kDa. It shares structural similarity with insulin and IGF-1 and belongs to the insulin-like growth factor family. In vivo, IGF-2 often binds to IGF-binding proteins (IGFBPs), which regulate its stability and activity. IGF-2 stimulates DNA synthesis and mitosis in various cell types, such as fibroblasts, muscle cells, and neural cells. It is commonly used in stem cell culture—including embryonic stem cells and mesenchymal stem cells—to sustain proliferative capacity. Under specific conditions and in combination with other factors, it can induce differentiation into muscle, cartilage, or neural cells. Additionally, IGF-2 plays regulatory roles in embryonic development and tumor cell growth.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing TFA, CAN, 5% Trehalose
Host:
HEK293
Molecular Weight:
7.5 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins