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Proteins and Peptides

Recombinant Human β-NGF

Product Sizes
50ug
£363.00
Y06941H-50UG
1mg
£2177.00
Y06941H-1MG
About this Product
SKU:
Y06941H
Application:
Bioactivity
Extra Details:
β-NGF (β-Nerve Growth Factor) is a neurotrophin belonging to the neurotrophic factor family. While structurally similar to other neurotrophins such as BDNF, NT-3, and NT-4/5, β-NGF specifically binds to the TrkA receptor (high affinity) and the p75NTR receptor (low affinity). In?in vitro?cultures, it primarily supports the survival, differentiation, and functional maintenance of specific neural populations, including sympathetic neurons, sensory neurons (e.g., dorsal root ganglion cells), and central cholinergic neurons (e.g., basal forebrain neurons). In downstream applications, β-NGF can be used in combination with stem cell cultures to induce the directed differentiation of neural precursor cells.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing 20mM Sodium acetate, 150mM NaCl, 5% Mannitol, 0.01%Tween 80, pH 5.5
Host:
HEK293
Molecular Weight:
13.4 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins