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Proteins and Peptides

Recombinant Human G-CSF

Product Sizes
50ug
£392.00
Y06201-50UG
1mg
£2177.00
Y06201-1MG
About this Product
SKU:
Y06201
Application:
Bioactivity
Extra Details:
G-CSF (Granulocyte Colony-Stimulating Factor), a member of the colony-stimulating factor family, is a single-chain glycoprotein with a molecular weight of approximately 19–22 kDa. As a crucial hematopoietic factor in cell culture, it specifically acts on myeloid hematopoietic cells—particularly the neutrophil lineage—to regulate their proliferation, differentiation, and function. By activating the G-CSF receptor (G-CSFR/CD114), it triggers signaling pathways such as JAK-STAT3, PI3K/Akt, and MAPK, thereby promoting the proliferation and differentiation of neutrophil precursor cells. Additionally, G-CSF enhances the function of mature neutrophils, inhibits their spontaneous apoptosis, and modulates inflammatory responses.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
Host:
Hamster
Molecular Weight:
18.7 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins