Recombinant Human NRG1-β1
Product Sizes
50ug
£335.00
Y01621H-50UG
1mg
£1580.00
Y01621H-1MG
About this Product
- SKU:
- Y01621H
- Application:
- Bioactivity
- Extra Details:
- NRG1-β1 (Neuregulin-1 β1), an isoform of Neuregulin-1 (NRG1), belongs to the epidermal growth factor (EGF) family. It regulates diverse cellular processes by binding to ErbB receptors (particularly ErbB3/ErbB4), activating downstream signaling pathways such as PI3K/Akt and MAPK, thereby supporting the survival and proliferation of neurons, cardiomyocytes, mammary epithelial cells, and other cell types. In the nervous system, it promotes Schwann cell differentiation and myelination; in neuronal cultures, NRG1-β1 modulates synapse formation and the expression of neurotransmitter receptors (e.g., NMDA receptors). In mammary cells, it helps regulate ductal morphogenesis.
- Format:
- Lyophilized powder
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
- Host:
- E. coli
- Molecular Weight:
- 7.5 kDa
- Purity:
- ≥95% by SDS-PAGE
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
