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Proteins and Peptides

Recombinant Human FGF-4

Product Sizes
50ug
£447.00
Y00921H-50UG
1mg
£2177.00
Y00921H-1MG
About this Product
SKU:
Y00921H
Application:
Bioactivity
Extra Details:
FGF-4 (Fibroblast Growth Factor 4), a member of the FGF family, is a secreted glycoprotein that activates downstream signaling pathways (such as MAPK and PI3K-AKT) by binding to its receptors (FGFRs). It promotes cell proliferation, differentiation, migration, and survival, playing a central role in embryonic development, mesoderm formation, and stem cell maintenance. In stem cells, it helps maintain pluripotency; for example, FGF-4 and LIF (Leukemia Inhibitory Factor) act synergistically to sustain the undifferentiated state of mouse embryonic stem cells (ESCs). Additionally, FGF-4 can promote the differentiation of specific cell types and is used in the culture of primary cells.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4
Host:
E. coli
Molecular Weight:
19.3 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins