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Proteins and Peptides

Recombinant Human BDNF

Product Sizes
50ug
£457.00
Y00201-50UG
1mg
£2244.00
Y00201-1MG
About this Product
SKU:
Y00201
Application:
Bioactivity
Extra Details:
BDNF (Brain-Derived Neurotrophic Factor) is a neurotrophic factor belonging to the neurotrophin family, characterized by a conserved cysteine knot structure and sharing homology with other neurotrophins such as NGF and NT-3. It is widely expressed in the central and peripheral nervous systems, with particularly high concentrations in brain regions like the hippocampus and cerebral cortex. BDNF plays crucial roles in neural growth, survival, synaptic plasticity, and cognitive function. It inhibits apoptotic pathways and enhances neuronal survival under conditions of serum deprivation or stress. When combined with factors like retinoic acid, BDNF can induce the differentiation of neural stem cells (NSCs) or PC12 cells into neurons.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
Host:
Hamster
Molecular Weight:
13.5 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins