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Proteins and Peptides

GMP Recombinant Human GM-CSF

Product Sizes
50ug
£523.00
G032-50UG
200ug
£3857.00
G032-200UG
About this Product
SKU:
G032
Application:
Bioactivity
Extra Details:
GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor), a member of the colony-stimulating factor (CSF) family, is a cytokine that regulates hematopoiesis and immune cell function. It is secreted by various cell types, including granulocytes, dendritic cells, T cells, and B cells, and primarily modulates cell proliferation, differentiation, survival, and function through the activation of specific signaling pathways such as JAK/STAT, MAPK, and PI3K.GM-CSF promotes the proliferation and differentiation of hematopoietic progenitor cells, and stimulates the lineage-specific differentiation and expansion of granulocytes (neutrophils, eosinophils) and macrophages. It also acts synergistically with cytokines such as IL-3 and SCF to enhance multi-lineage hematopoiesis.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
Host:
Hamster
Molecular Weight:
14.5 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins