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Proteins and Peptides

GMP Recombinant Human M-CSF

Product Sizes
50ug
£651.00
G029-50UG
200ug
£4945.00
G029-200UG
About this Product
SKU:
G029
Application:
Bioactivity
Extra Details:
M-CSF (Macrophage Colony-Stimulating Factor) is an important glycoprotein cytokine that exists as a disulfide-linked homodimer. It plays a key role in regulating the proliferation, differentiation, and survival of the monocyte-macrophage lineage. M-CSF promotes the proliferation of monocytes/macrophages, supports the differentiation of hematopoietic stem cells into monocytes and their subsequent development into macrophages, and enhances macrophage survival through anti-apoptotic signaling (e.g., upregulation of Bcl-2). Additionally, it modulates functional polarization and influences macrophage phenotype.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
Host:
E. coli
Molecular Weight:
18.4 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins