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Proteins and Peptides

GMP Recombinant Human TGF-β1

Product Sizes
50ug
£763.00
G016-50UG
200ug
£5653.00
G016-200UG
About this Product
SKU:
G016
Application:
Bioactivity
Extra Details:
TGF-β1 (Transforming Growth Factor-β1) is a multifunctional cytokine belonging to the TGF-β superfamily. It inhibits the growth of most epithelial, endothelial, and hematopoietic cells by inducing cell cycle arrest in the G1 phase. In stem cell culture, TGF-β1 can direct the differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, or adipocytes. In organoid culture systems, it regulates extracellular matrix (ECM) formation and influences tissue organization. Additionally, TGF-β1 exhibits immunomodulatory effects by suppressing the activation of T cells, B cells, NK cells, and macrophages, thereby reducing inflammatory responses. In co-culture systems—such as those involving immune and tumor cells—TGF-β1 can help mimic an immune-suppressive microenvironment.
Format:
Lyophilized powder
Formulation:
Lyophilized from a 0.22 um filtered solution containing 0.085% TFA, 30% ACN, 5% mannitol, pH 2.5
Host:
Hamster
Molecular Weight:
12.8 kDa
Purity:
≥95% by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins