GMP Recombinant Human PDGF-BB
Product Sizes
50ug
£621.00
G001-50UG
1mg
£4645.00
G001-1MG
About this Product
- SKU:
- G001
- Application:
- Bioactivity
- Extra Details:
- PDGF-BB (Platelet-Derived Growth Factor-BB) is an important growth factor belonging to the platelet-derived growth factor (PDGF) family. It consists of two identical B chains linked by disulfide bonds to form a homodimer and is one of the most biologically potent isoforms in the PDGF family. PDGF-BB activates PDGF receptors (PDGFR-α and PDGFR-β) on the cell membrane, triggering downstream signaling pathways that promote the proliferation of various cell types—particularly fibroblasts, smooth muscle cells, glial cells, and mesenchymal stem cells. Additionally, in processes such as wound healing, angiogenesis, and tissue regeneration, PDGF-BB acts as a chemoattractant, guiding cells such as fibroblasts and pericytes to sites of injury to facilitate tissue repair. It also contributes to the stabilization of newly formed blood vessels and works synergistically with VEGF to promote vascular formation.
- Format:
- Lyophilized powder
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4
- Host:
- Hamster
- Molecular Weight:
- 12.2 kDa
- Purity:
- ≥95% by SDS-PAGE
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
