HEK293-FOLR1 Cells - Transformed cell lines
Product Sizes
1 each
£6257.00
305425-1EACH
About this Product
- SKU:
- 305425
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Extra Details:
- Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The HEK293-FOLR1 cell line is a stable recombinant HEK293 cell line engineered to express the FOLR1 receptor at a medium-high level, approximately 15,000 molecules per cell. This cell line was developed using inscreenex's landing pad technology, ensuring precise and reproducible integration of the FOLR1 gene at a specific, pre-validated genomic locus. FOLR1, also known as Folate Receptor Alpha (FRA Alpha) or FBP, is a GPI-anchored membrane protein with a strong affinity for folate, facilitating its transport into cells. FOLR1 is markedly overexpressed in certain cancers, such as ovarian, breast, and non-small cell lung cancers, making it a significant target for immuno-oncology therapies, including CAR T cell therapies and bispecific antibodies.The expression of FOLR1 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cytion
- Type:
- Cells: Cell Lines
- Manufacturer's Data Sheet:01917e785a6b74958dbc88a13cb32d6d
