CHO-CCR8 Cells - Hamster cell lines
Product Sizes
1 each
£6257.00
305418-1EACH
About this Product
- SKU:
- 305418
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Extra Details:
- Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-CCR8 cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line engineered to express the CCR8 receptor at a medium-high level, approximately 8,000 molecules per cell. This cell line was developed using advanced landing pad technology, ensuring precise and reproducible integration of the CCR8 gene at a specific, pre-validated genomic locus. CCR8, also known as CHEMR1 or CDw198, is a G protein-coupled receptor (GPCR) expressed on various immune cells, particularly regulatory T cells (Tregs). CCR8 plays a critical role in the immune suppression process within the tumor microenvironment, facilitating tumor cells' ability to evade immune detection. As such, targeting CCR8 has become a promising strategy in cancer immunotherapy to reduce Treg-mediated suppression and enhance anti-tumor immunity. The expression of CCR8 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cytion
- Type:
- Cells: Cell Lines
- Manufacturer's Data Sheet:01917e6f00347f10a3a7d3c153179bbc
