CHO-B7H3 Cells - Hamster cell lines
Product Sizes
1 each
£6257.00
305417-1EACH
About this Product
- SKU:
- 305417
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Extra Details:
- Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-B7H3 cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line engineered to express the B7-H3 receptor at a high level, approximately 430,000 molecules per cell. This cell line was developed using innovative landing pad technology, which ensures precise and reproducible integration of the B7-H3 gene at a specific, pre-validated genomic locus. B7-H3, also known as CD276, is a member of the B7 family of immune checkpoint proteins and is overexpressed in various cancers. It plays a critical role in immune evasion by tumor cells and is associated with poor prognosis in cancer patients. This makes B7-H3 a promising target for cancer immunotherapy, particularly in the development of checkpoint inhibitors and antibody-drug conjugates. The expression of B7-H3 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable and consistent receptor density across the cell population.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cytion
- Type:
- Cells: Cell Lines
- Manufacturer's Data Sheet:01917e6ef9da773ab533ed7ffe49a231
