RM-1 Cells - Mouse cell lines
Product Sizes
1 each
£879.00
305168-1EACH
About this Product
- SKU:
- 305168
- Additional Names:
- RM1
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Extra Details:
- The RM-1 cell line is a fibroblast-like model derived from the embryonic prostate tissue of C57BL/6 mouse embryos. These cells were isolated from 17-day-old urogenital sinus cells and infected with the Zipras/myc9 retrovirus, containing the oncogenes v-Ha-Ras and v-Myc. RM-1 cells exhibit high tumorigenic potential, forming poorly differentiated mouse prostate carcinomas with high frequency. RM-1 cells are positive for cytokeratin 18 mRNA and immunoreactive to cytokeratin-specific antiserum, indicating epithelial origin. They demonstrate significant mitogenic response to testosterone, with approximately a two-fold increase in cell number under serum-free conditions. This cell line maintains stable androgen receptor numbers and binding kinetics across multiple passages, making it a valuable model for studying androgen sensitivity and prostate cancer progression.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cytion
- Type:
- Cells: Cell Lines
- Manufacturer's Data Sheet:997c0d34c4ff4ca983e7666f47521c42
