WERI-Rb-1 Cells - Head-Neck cancer cell lines
Product Sizes
1 each
£607.00
300632-1EACH
About this Product
- SKU:
- 300632
- Additional Names:
- WERI-RB-1, WERI-Rb 1, WERI-Rb1, WERI-RB1, WERI Rb-1, WERIRb1, WERI, Wills Eye Research Institute-Retinoblastoma-1
- Application:
- Tissue Culture
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Extra Details:
- The WERI-Rb-1 cell line is derived from a retinoblastoma, a rare malignant tumor of the retina that typically manifests in early childhood. This cell line was established to provide a consistent and replicable model for the study of retinoblastoma biology, offering insights into the genetic, molecular, and cellular mechanisms underlying this form of cancer. WERI-Rb-1 cells are particularly valued in oncological research for their utility in investigating the pathophysiological processes and potential therapeutic targets for retinoblastoma. WERI-Rb-1 cells exhibit characteristics typical of retinoblastoma, including the expression of neuronal markers and the capability to form cell aggregates resembling Flexner-Wintersteiner rosettes, a hallmark of retinoblastoma histology. These cells have been used extensively to study the role of oncogenes and tumor suppressor genes in cancer development, with a focus on the RB1 gene, mutations of which are pivotal in the etiology of retinoblastoma. Furthermore, WERI-Rb-1 serves as an important tool in the evaluation of chemotherapeutic agents and novel drug delivery systems aimed at improving treatment outcomes for retinoblastoma patients.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cytion
- Type:
- Cells: Cell Lines
- Manufacturer's Data Sheet:35bb513bda7647989f103eef03ca101d
