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Antibodies

ERBB3 Recombinant Monoclonal Antibody

Product Sizes
50 ul
£235.00
CSB-RA937008A0HU-50UL
100 ul
£392.00
CSB-RA937008A0HU-100UL
About this Product
SKU:
CSB-RA937008A0HU
Additional Names:
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3), ERBB3, HER3
Application:
ELISA, Immunofluorescence
Buffer:
phosphate buffered saline, 150mm nacl
translate.label.attr.clone:
6F6
Clonality:
Recombinant Monoclonal
Extra Details:
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134).
Immunogen:
A synthesized peptide derived from human ErbB3
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Recombinant Antibodies
Immunofluorescence staining of MCF7 Cells with CSB-RA937008A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).