EPAS1 Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA904931A0HU-50UL
100 ul
£392.00
CSB-RA904931A0HU-100UL
About this Product
- SKU:
- CSB-RA904931A0HU
- Additional Names:
- Endothelial PAS domain-containing protein 1 (EPAS-1) (Basic-helix-loop-helix-PAS protein MOP2) (Class E basic helix-loop-helix protein 73) (bHLHe73) (HIF-1-alpha-like factor) (HLF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha) (Member of PAS protein 2) (PAS domain-containing protein 2), EPAS1, BHLHE73 HIF2A MOP2 PASD2
- Application:
- ELISA, Immunofluorescence
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 6A9
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
- Immunogen:
- A synthesized peptide derived from human HIF-2 alpha
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:EPAS1-Antibody-12928882.html
