AGO3 Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA875700A0HU-50UL
100 ul
£392.00
CSB-RA875700A0HU-100UL
About this Product
- SKU:
- CSB-RA875700A0HU
- Additional Names:
- Protein argonaute-3UniRule annotation, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3UniRule annotation, AGO3, EIF2C3
- Application:
- ELISA
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 4F7
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).
- Immunogen:
- A synthesized peptide derived from human AGO3
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:AGO3-Antibody-12923392.html
