ADAM17 Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA797631A0HU-50UL
100 ul
£392.00
CSB-RA797631A0HU-100UL
About this Product
- SKU:
- CSB-RA797631A0HU
- Additional Names:
- Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b), ADAM17, CSVP TACE
- Application:
- ELISA, Immunofluorescence
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 5A1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
- Immunogen:
- A synthesized peptide derived from human ADAM17
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:ADAM17-Antibody-12928874.html
