Phospho-SMAD2 (S255) Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA618017A255PHHU-50UL
100 ul
£392.00
CSB-RA618017A255PHHU-100UL
About this Product
- SKU:
- CSB-RA618017A255PHHU
- Additional Names:
- Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2
- Application:
- ELISA, Immunofluorescence
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 2A12
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
- Immunogen:
- A synthesized peptide derived from human Phospho-SMAD2 (S255)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Phospho-SMAD2--S255--Antibody-12921435.html
