Phospho-SMC1A (S957) Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA614804A957PHHU-50UL
100 ul
£392.00
CSB-RA614804A957PHHU-100UL
About this Product
- SKU:
- CSB-RA614804A957PHHU
- Additional Names:
- Structural maintenance of chromosomes protein 1A, SMC protein 1A, SMC-1-alpha, Sb1.8, SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 1F9
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
- Immunogen:
- A synthesized peptide derived from human Phospho-SMC1A (S957)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Phospho-SMC1A--S957--Antibody-12921418.html
