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Antibodies

TYR Recombinant Monoclonal Antibody

Product Sizes
50 ul
£235.00
CSB-RA567167A0HU-50UL
100 ul
£392.00
CSB-RA567167A0HU-100UL
About this Product
SKU:
CSB-RA567167A0HU
Additional Names:
Tyrosinase (EC 1.14.18.1) (LB24-AB) (Monophenol monooxygenase) (SK29-AB) (Tumor rejection antigen AB), TYR
Application:
ELISA, Immunofluorescence
Buffer:
phosphate buffered saline, 150mm nacl
translate.label.attr.clone:
6B2
Clonality:
Recombinant Monoclonal
Extra Details:
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Immunogen:
A synthesized peptide derived from human Tyrosinase
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Recombinant Antibodies
Immunofluorescence staining of MCF7 Cells with CSB-RA567167A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).