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Antibodies

MEN1 Recombinant Monoclonal Antibody

Product Sizes
50 ul
£235.00
CSB-RA242999A0HU-50UL
100 ul
£392.00
CSB-RA242999A0HU-100UL
About this Product
SKU:
CSB-RA242999A0HU
Additional Names:
Menin, MEN1, SCG2
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline, 150mm nacl
translate.label.attr.clone:
8G11
Clonality:
Recombinant Monoclonal
Extra Details:
Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Immunogen:
A synthesized peptide derived from human Menin
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Recombinant Antibodies