SIRT5 Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA156557A0HU-50UL
100 ul
£392.00
CSB-RA156557A0HU-100UL
About this Product
- SKU:
- CSB-RA156557A0HU
- Additional Names:
- NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 9H12
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
- Immunogen:
- A synthesized peptide derived from human SIRT5
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:SIRT5-Antibody-12928753.html
