Phospho-PTPN11 (Y542) Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA019025A542PHHU-50UL
100 ul
£392.00
CSB-RA019025A542PHHU-100UL
About this Product
- SKU:
- CSB-RA019025A542PHHU
- Additional Names:
- Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2
- Application:
- ELISA, Immunoprecipitation, Western Blot
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 2E2
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
- Immunogen:
- A synthesized peptide derived from human Phospho-PTPN11 (Y542)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Phospho-PTPN11--Y542--Antibody-12921413.html
