PTGS2 Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA018986A0HU-50UL
100 ul
£392.00
CSB-RA018986A0HU-100UL
About this Product
- SKU:
- CSB-RA018986A0HU
- Additional Names:
- Prostaglandin G/H synthase 2, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2
- Application:
- ELISA
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 4A9
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
- Immunogen:
- A synthesized peptide derived from human PTGS2
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:PTGS2-Antibody-12923422.html
