Phospho-Histone H2AX (S139) Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA010097A139PHHU-50UL
100 ul
£392.00
CSB-RA010097A139PHHU-100UL
About this Product
- SKU:
- CSB-RA010097A139PHHU
- Additional Names:
- Histone H2AX, H2a/x, Histone H2A.X, H2AFX, H2AX
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 1F10
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
- Immunogen:
- A synthesized peptide
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Phospho-Histone-H2AX--S139--Antibody-12783051.html
