Phospho-ERN1 (S724) Recombinant Monoclonal Antibody
Product Sizes
50 ul
£235.00
CSB-RA007795A724PHHU-50UL
100 ul
£392.00
CSB-RA007795A724PHHU-100UL
About this Product
- SKU:
- CSB-RA007795A724PHHU
- Additional Names:
- Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, ERN1
- Application:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 1F12
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).
- Immunogen:
- A synthesized peptide derived from human Phospho-ERN1 (S724)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Phospho-ERN1--S724--Antibody-12921408.html
