TP53 (Ab-18) Antibody
Product Sizes
100 ul
£332.00
CSB-PA992550-100UL
About this Product
- SKU:
- CSB-PA992550
- Additional Names:
- Antigen NY-CO-13 antibody; BCC7 antibody; Cellular tumor antigen p53 antibody; FLJ92943 antibody; LFS1 antibody; Mutant tumor protein 53 antibody; p53 antibody; p53 tumor suppressor antibody; P53_HUMAN antibody; Phosphoprotein p53 antibody; Tp53 antibody; Transformation related protein 53 antibody; TRP53 antibody; tumor antigen p55 antibody; Tumor protein 53 antibody; Tumor protein p53 antibody; Tumor suppressor p53 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Lin T, et al. (2005) Nat Cell Biol; 7(2): 165-71. Vega FM, et al. (2004) Mol Cell Biol; 24(23): 10366-80. Li J, et al. (2004) J Biol Chem; 279(40): 41275-9. Wang J, et al. (2004) J Biol Chem; 279(38): 39584-92.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa. 16~20 (Q-E-T-F-S) derived from Human p53.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TP53-Ab-18-Antibody-11082957.html
