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Antibodies

TNFRSF13C Antibody

Product Sizes
50 ul
£186.00
CSB-PA984896-50UL
100 ul
£334.00
CSB-PA984896-100UL
About this Product
SKU:
CSB-PA984896
Additional Names:
B cell activating factor receptor antibody; B-cell-activating factor receptor antibody; BAFF R antibody; BAFF receptor antibody; BAFF-R antibody; BAFFR antibody; BLyS receptor 3 antibody; BlySR3 antibody; BR 3 antibody; BR3 antibody; BROMIX antibody; CD 268 antibody; CD268 antibody; CD268 antigen antibody; CVID4 antibody; MGC138235 antibody; OTTHUMP00000028746 antibody; Prolixin antibody; TNFRSF 13C antibody; Tnfrsf13c antibody; TR13C_HUMAN antibody; Tumor necrosis factor receptor subunit member 13C antibody; Tumor necrosis factor receptor superfamily member 13C antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human TNFRSF13C
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody