NCKAP1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA982423-50UL
100 ul
£334.00
CSB-PA982423-100UL
About this Product
- SKU:
- CSB-PA982423
- Additional Names:
- FLJ11291 antibody; KIAA0587 antibody; Membrane associated protein HEM2 antibody; Membrane-associated protein HEM-2 antibody; MGC8981 antibody; NAP 1 antibody; NAP1 antibody; NAP125 antibody; NCK associated protein 1 antibody; NCK associated protein antibody; Nck-associated protein 1 antibody; Nckap1 antibody; NCKP1_HUMAN antibody; OTTHUMP00000163460 antibody; OTTHUMP00000163461 antibody; p125Nap1 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human NCKAP1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NCKAP1-Antibody-11105129.html
