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Antibodies

Phospho-IGF2R (Ser2409) Antibody

Product Sizes
100 ul
£402.00
CSB-PA973142-100UL
About this Product
SKU:
CSB-PA973142
Additional Names:
300 kDa mannose 6 phosphate receptor antibody; 300 kDa mannose 6-phosphate receptor antibody; Cation independent mannose 6 phosphate receptor antibody; Cation-independent mannose-6-phosphate receptor antibody; CD222 antibody; CD222 antigen antibody; CI Man 6 P receptor antibody; CI Man-6-P receptor antibody; CI MPR antibody; CI-M6PR antibody; CI-MPR antibody; CIMPR antibody; IGF 2 receptor antibody; IGF 2R antibody; IGF II receptor antibody; IGF-II receptor antibody; IGF2 receptor antibody; Igf2r antibody; Insulin like growth factor 2 receptor antibody; Insulin like growth factor II receptor antibody; Insulin-like growth factor 2 receptor antibody; Insulin-like growth factor II receptor antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; mannose 6 phosphate receptor antibody; mannose 6 phosphate receptor, cation independent antibody; MPR 300 antibody; MPR300 antibody; MPRI antibody; MPRI_HUMAN antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Morgan D.O., Nature 329:301-307(1987). Oshima A., J. Biol. Chem. 263:2553-2562(1988). Killian J.K., Mamm. Genome 10:74-77(1999)
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of Serine 2409(Q-D-S(p)-E-D) derived from Human IGF2R.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody