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Antibodies

PLG Antibody

Product Sizes
100 ul
£332.00
CSB-PA970985-100UL
About this Product
SKU:
CSB-PA970985
Additional Names:
Plasmin antibody; Plasmin heavy chain A antibody; Plasmin light chain B antibody; Plasminogen antibody; PLG antibody; PLMN_HUMAN antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. Petersen T.E., J. Biol. Chem. 265:6104-6111(1990). Forsgren M., FEBS Lett. 213:254-260(1987). Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from N-terminal of Human PLG.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody