GCH1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA964562-50UL
100 ul
£334.00
CSB-PA964562-100UL
About this Product
- SKU:
- CSB-PA964562
- Additional Names:
- dystonia 14 antibody; DYT 5 antibody; DYT14 antibody; DYT5 antibody; DYT5a antibody; GCH 1 antibody; GCH antibody; Gch1 antibody; GCH1_HUMAN antibody; GTP CH 1 antibody; GTP CH I antibody; GTP cyclohydrolase 1 (dopa responsive dystonia) antibody; GTP cyclohydrolase 1 antibody; GTP cyclohydrolase I antibody; GTP-CH-I antibody; GTPCH 1 antibody; GTPCH1 antibody; Guanosine 5' triphosphate cyclohydrolase I antibody; HPABH4B antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human GCH1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GCH1-Antibody-11103098.html
