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Antibodies

NCAM1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA960581-100UL
About this Product
SKU:
CSB-PA960581
Additional Names:
antigen MSK39 identified by monoclonal antibody 5.1H11 antibody; antigen recognized by monoclonal antibody 5.1H11 antibody; CD56 antibody; cell adhesion molecule, neural, 1 antibody; MSK 39 antibody; MSK39 antibody; N-CAM-1 antibody; NCAM 1 antibody; NCAM antibody; NCAM C antibody; NCAM-1 antibody; NCAM1 antibody; NCAM1_HUMAN antibody; NCAMC antibody; Neural cell adhesion molecule 1 antibody; Neural cell adhesion molecule NCAM antibody; OTTHUMP00000235666 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3). Cunningham, B. A. et al. (1987) Science 236, 799-806. Seidenfaden, R. et al. (2003) Mol. Cell. Biol. 23, 5908-5918. Robertson, M.J. and Ritz, J. (1990) Blood 76, 2421-2438.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.850~854(Q-T-K-E-N)derived from Human CD56(NCAM).
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody