ABCC5 Antibody
Product Sizes
50 ul
£186.00
CSB-PA951195-50UL
100 ul
£334.00
CSB-PA951195-100UL
About this Product
- SKU:
- CSB-PA951195
- Additional Names:
- ABC 33 antibody; ABC33 antibody; ABCC 5 antibody; Abcc5 antibody; ATP binding cassette sub family C (CFTR/MRP) member 5 antibody; ATP binding cassette sub family C member 5 antibody; ATP-binding cassette sub-family C member 5 antibody; Canalicular multispecific organic anion transporter C antibody; DKFZp686C1782 antibody; EST277145 antibody; MOAT C antibody; MOAT-C antibody; MOATC antibody; MRP 5 antibody; MRP5_HUMAN antibody; Multi specific organic anion tranporter C antibody; Multi-specific organic anion transporter C antibody; Multidrug resistance associated protein 5 antibody; Multidrug resistance-associated protein 5 antibody; pABC 11 antibody; pABC11 antibody; SMRP antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human ABCC5
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ABCC5-Antibody-11103279.html
