Mapt Antibody
Product Sizes
100 ul
£332.00
CSB-PA945056-100UL
About this Product
- SKU:
- CSB-PA945056
- Additional Names:
- Mapt antibody; Mtapt antibody; Tau antibody; Microtubule-associated protein tau antibody; Neurofibrillary tangle protein antibody; Paired helical filament-tau antibody; PHF-tau antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Johnson , G.V. and Stoothoff , W.H. (2004) J. Cell Sci. 117, 5721-5729. Hanger, D. P. et al. (1998) J. Neurochem. 71, 2465-2476. Bramblett, G. T. et al. (1993) Neuron 10, 1089-1099.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa. 725-729(T-G-S-I-D) derived from Rat Tau
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Mapt-Antibody-11083270.html
