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Antibodies

BIN1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA942155-50UL
100 ul
£334.00
CSB-PA942155-100UL
About this Product
SKU:
CSB-PA942155
Additional Names:
AMPH 2 antibody; AMPH2 antibody; Amphiphysin 2 antibody; Amphiphysin II antibody; Amphiphysin like protein antibody; amphiphysin-like antibody; Amphiphysin-like protein antibody; AMPHL antibody; Bin1 antibody; BIN1_HUMAN antibody; Box Dependant MYC Interacting Protein 1 antibody; Box-dependent myc-interacting protein 1 antibody; Bridging integrator 1 antibody; DKFZp547F068 antibody; MGC10367 antibody; MGC105358 antibody; Myc box dependent interacting protein 1 antibody; Myc box-dependent-interacting protein 1 antibody; SH3P9 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Host:
Rabbit
Immunogen:
Fusion protein of Human BIN1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody