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Antibodies

MUC1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA941558-50UL
100 ul
£334.00
CSB-PA941558-100UL
About this Product
SKU:
CSB-PA941558
Additional Names:
mucin 1, cell surface associated
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human MUC1(NT)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody