Phospho-CASP9 (Thr125) Antibody
Product Sizes
100 ul
£402.00
CSB-PA938158-100UL
About this Product
- SKU:
- CSB-PA938158
- Additional Names:
- APAF-3 antibody; Apoptotic protease Mch-6 antibody; Apoptotic protease-activating factor 3 antibody; CASP-9 antibody; CASP9 antibody; CASP9_HUMAN antibody; Caspase 9 antibody; Caspase-9 subunit p10 antibody; ICE-LAP6 antibody; ICE-like apoptotic protease 6 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. Duan H., J. Biol. Chem. 271:16720-16724(1996). Srinivasula S.M., J. Biol. Chem. 271:27099-27106(1996). Hadano S., Mamm. Genome 10:757-760(1999)
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 125 (P-E-T(p)-P-R) derived from Human Caspase 9.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Phospho-CASP9-Thr125-Antibody-11084115.html
