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Antibodies

PARD3 Antibody

Product Sizes
100 ul
£332.00
CSB-PA921456-100UL
About this Product
SKU:
CSB-PA921456
Additional Names:
agouti signaling protein antibody; ASIP antibody; Atypical PKC isotype specific interacting protein antibody; Atypical PKC isotype-specific-interacting protein antibody; Baz antibody; bazooka antibody; Coagulation factor II receptor-like 2 antibody; CTCL tumor antigen se2-5 antibody; F2rl2 antibody; PAR-3 antibody; par-3 family cell polarity regulator alpha antibody; par-3 family cell polarity regulator antibody; PAR3 alpha antibody; par3 antibody; PAR3-alpha antibody; PARD-3 antibody; Pard3 antibody; PARD3_HUMAN antibody; PARD3A antibody; Partitioning defective 3 homolog antibody; Partitioning-defective 3 homolog antibody; Partitioning-defective protein 3; C. elegans; homolog of antibody; SE2-5L16 antibody; SE2-5LT1 antibody; SE2-5T2 antibody; Thrombin receptor-like 2 antibody
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons. Joberty G., Nat. Cell Biol. 2:531-539(2000). Fang C.M., Cell Res. 11:223-229(2001). Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human PARD3.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody